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Clinical Articles


RenalGuard® is designed to reduce the toxic effects that contrast media can have on the kidneys, which may lead to a reduction in the incidence of Contrast-Induced Nephropathy (CIN) in at-risk patients.

The following papers and abstracts discuss the use of RenalGuard Therapy® in the prevention of Contrast-Induced Kidney Injury (CIN).


Barbanti, Marco


Optimisation and simplification of transcatheter aortic valve implantation therapy


Expert Review of Cardiovascular Therapy

Luckraz, Heyman

The use of the RenalGuard system in cardiac surgery with cardiopulmonary bypass: a first in man prospective, observational, feasibility pilot study


Prasad, Anand

Use of the RenalGuard system to prevent contrast-induced AKI: A meta-analysis

Journal of Interventional Cardiology

Bartorelli, Antonio L ; Marenzi, Giancarlo

High Urine Output With Matched Hydration for CI-AKI Prevention “Salus Per Aquam” (Health Through Water)

JACC: Cardiovascular Interventions

Putzu et al.

Prevention of Contrast-Induced Acute Kidney Injury by Furosemide With Matched Hydration in Patients Undergoing Interventional Procedures

JACC: Cardiovascular Interventions

Banai, Shmuel

Prevention of post procedural acute kidney injury in the catheterization laboratory in a real-world population

International Journal of Cardiology

Visconti, Gabriella

RenalGuard System for the prevention of acute kidney injury in patients undergoing transcatheter aortic valve implantation


Briguori, Carlo

RenalGuard system in high-risk patients for contrast-induced Acute Kidney Injury

American Heart Journal

Barbanti et al.

Acute Kidney Injury With the RenalGuard System in Patients Undergoing Transcatheter Aortic Valve Replacement

JACC: Cardiovascular Interventions

T. Usmiani

AKIGUARD (acute kidney injury guarding device) independent, randomized and controlled trial on contrast-induced acute kidney injury prevention in the cath lab: in-hospital and one year outcomes

European Heart Journal ( 2014 )

Marenzi, Giancarlo, Bartorelli, Antonio, et al.

Prevention of Contrast Nephropathy by Furosemide with Matched Hydration: The MYTHOS Trial

JACC: Cardiovascular Interventions

Halpert, Andrew

RenalGuard – an old idea with a modern twist: preventing contrast-induced nephropathy through induced diuresis with matched replacement

EuroPCR 2012

Bertelli, Luca, et al.

Comparison Of Renalguard System, Continuous Venovenous Hemofiltration And Hydration In High-Risk Patients For Contrast-Induced Nephropathy

Journal of the American College of Cardiology

Briguori, Carlo, et al.

Renal Insufficiency After Contrast Media Administration Trial II (REMEDIAL II)


Dorval, Jean-Frarncois, et al.

Feasibility study of the RenalGuard™ balanced hydration system: A novel strategy for the prevention of contrast-induced nephropathy in high risk patients

International Journal of Cardiology

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